Biotinylated Anti-CXCR3 antibody(DM208); Rabbit mAb
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| Amount : | 100 µg |
| Isotype : | IgG |
| Purification : | Purified from cell culture supernatant by affinity chromatography |
| Content : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage condition : | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Gene : | CXCR3 |
| Uniprot ID : | P49682 |
| Alternative Name : | CD182; CD183; CKR-L2; CMKAR3; GPR9; IP10-R; Mig-R; MigR |
This gene encodes a G protein-coupled receptor with selectivity for three chemokines; termed CXCL9:Mig (monokine induced by interferon-g); CXCL10:IP10 (interferon-g-inducible 10 kDa protein) and CXCL11:I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic; most notably integrin activation; cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine; CXCL4:PF4 (PMID:12782716). [provided by RefSeq; Jun 2011]
ELISA 1:5000-10000; Flow Cyt 1:100
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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