Biotinylated Anti-CD38 antibody(DM30), Rabbit mAb
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| Amount : | 100 µg |
| Purification : | Purified from cell culture supernatant by affinity chromatography |
| Content : | Not Sterile |
| Storage condition : | Store at 2 °C-8 °C for 6 months |
| Alternative Name : | T10, cADPr hydrolase 1 |
CD antigen CD38 is also known as ADP-ribosyl cyclase 1, which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+ to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2+. The loss of CD38 function is associated with impaired immune responses, metabolic disturbances, and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection, leukemias, myelomas, solid tumors, type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia.
ELISA 1/5000-10000;FACS 1/100
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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