Biotinylated Anti-B7-H3 antibody(DM53), Rabbit mAb
Figure 1. 1e5 of Expi 293 cell line were stained with 100 μL of 1:1000 diluted Biotinylated Anti-B7-H3 antibody (DM53), Rabbit mAb (Blue histogram) or isotype control (Red histogram) respectively, washed and then stained with Streptavidin APC. The experimental samples were analyzed by flow cytometry.
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| Amount : | 100 µg |
| Purification : | Purified from cell culture supernatant by affinity chromatography |
| Content : | Not Sterile |
| Storage condition : | Store at 2 °C-8 °C for 6 months |
| Alternative Name : | B7-H3, CD276, B7 homolog 3, B7H3 |
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
ELISA 1/5000-10000;FACS 1/1000
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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