Biotinylated Anti-41BB Ligand antibody(DM68), Rabbit mAb
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| Format : | Liquid |
| Amount : | 100 µg |
| Purification : | Purified from cell culture supernatant by affinity chromatography |
| Content : | Not Sterile |
| Storage condition : | Store at 2 °C-8 °C for 6 months |
| Alternative Name : | 4-1BB Ligand,TNFSF9,CD137L,CD137 L,CD137-L,41BBL,4-1BBL,41BB-L, |
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.
ELISA 1/5000-10000;FACSÂ 1/100
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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