Azide free, Anti-CD107a / LAMP-1 Monoclonal Antibody (Clone:B-T47)(Discontinued)

Product code: 30-1026

Clone name : B-T47
Clonality : Monoclonal
Application : FACS
Reactivity : Human

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For estimated delivery dates, please contact us at [email protected]


Amount : 0.1 mg
Isotype : Mouse IgG1
Purification : Purified by protein-A affinity chromatography
Storage condition : Store at 2-8°C. Do not freeze.
Gene : LAMP1
Gene ID : 3916
Uniprot ID : P11279
Alternative Name : LAMP1
Immunogen Information : U937 human Caucasian hystiocytic lymphoma cell line

CD107a (lysosome-associated membrane protein-1, LAMP-1), together with LAMP-2, is a major constituent of lysosomal membrane, 1-2% of total CD107a is found also on the plasma membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Increased CD107a immunoreactivity is observed in neurones, and in glial cells surrounding senile plaques in Alzheimers disease cases and is localized mainly in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution. CD107a is a good marker of mast cell activation.

Flow Cytometry Recommended dilution:1 µg/ml
Immunohistochemistry Immunocytochemistry

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cell membrane, Endosome membrane, Lysosome membrane, Late endosome
Post transnational modification: O- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans. The glycosylation of N-76 is essential for Lassa virus entry into cells.
BioGrid: 110110. 63 interactions.
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