APC Conjugated Anti-CD88 / C5aR Monoclonal Antibody (Clone:S5/1)

Product code: 30-1531AC

Clone name : S5/1
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : APC

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100 tests
$499.00 

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]


Amount : 100 tests
Isotype : Mouse IgG2a
Purification : Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Content : Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : C5AR1
Gene ID : 728
Uniprot ID : P21730
Alternative Name : C5AR1, C5AR, C5R1
Immunogen Information : Recombinant N-terminal peptide (Asp15-Asp27) of human C5aR

CD88 / C5aR is a G protein-coupled seven membrane-spanning protein serving as a receptor for C5a component of the complement cascade, and is expressed mainly by monocytes, macrophages, neutrophils, eosinophils, and mast cells, but also e.g. by hepatocytes, glial cells, vascular endothelial cells, or cardiomyocytes. The binding of C5a to CD88 is associated with inflammatory response, including superoxide anion production, chemotaxis, and increased production of acute phase proteins. Expression of CD88 on synovial mast cells and their C5a-mediated degranulation plays a role in pathogenesis of rheumatoid arthritis.

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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