APC Conjugated Anti-CD49f Monoclonal Antibody (Clone:GoH3)

Product code: 30-2772AC

Clone name : GoH3
Clonality : Monoclonal
Application : FACS
Conjugate : APC

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100 Tests
$499.00 

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Format : Purified
Amount : 100 Tests
Isotype : Rat IgG2a
Purification : Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Content : Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage condition : Store at 2-8°C protected from light. Do not freeze.
Gene : ITGA6
Gene ID : 3655
Uniprot ID : P23229
Alternative Name : integrin subunit alpha 6 ITGA6, VLA6alpha, platelet gpIc, integrin subunit alpha 6
Immunogen Information : mouse mammary tumor cells

CD49f (alpha 6 integrin) is a type I transmembrane glycoprotein, which noncovalently associates with CD29 (beta 1 integrin) to form VLA-6, and with CD104 (beta 4 integrin) to form alpha6/beta4 integrin complex. CD49f is expressed on platelets, megakaryocytes, monocytes, T cells and thymocytes. It is widely expressed on many cultured adherent cell lines and on epithelia in non-lymphoid tissues. It is important for adhesion to laminins, invasin, and merosin, hence also for cell migration, embryogenesis, metastasis, formation of hemidesmosomes in epithelia, and other processes.
Specificity :The rat monoclonal antibody GoH3 recognizes an extracellular epitope of CD49f, an alpha6 integrin subunit.

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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