Anti-Wilm's Tumor 1 (WT1) (Wilm's Tumor & Mesothelial Marker) Monoclonal Antibody(Clone: rWT1/857)

Name: Anti-Wilm's Tumor 1 (WT1) (Wilm's Tumor & Mesothelial Marker) Monoclonal Antibody(Clone: rWT1/857)
Brand: Abeomics
SKU: 36-3376
Price: 520.0000 USD
Availability: InStock
Rating: 4.4 (10 reviews)

Fig. 1: Formalin-fixed, paraffin-embedded human Testis stained with Wilm's Tumor Mouse Recombinant Monoclonal Antibody (rWT1/857).

Anti-Wilm's Tumor 1 (WT1) (Wilm's Tumor & Mesothelial Marker) Monoclonal Antibody(Clone: rWT1/857)

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Fig. 1: Formalin-fixed, paraffin-embedded human Testis stained with Wilm's Tumor Mouse Recombinant Monoclonal Antibody (rWT1/857).

Fig. 2: Formalin-fixed, paraffin-embedded human Mesothelioma stained with Wilm's Tumor Mouse Recombinant Monoclonal Antibody (rWT1/857).

Fig. 3: Formalin-fixed, paraffin-embedded Rat Testis stained with Wilm's Tumor Mouse Recombinant Monoclonal Antibody (rWT1/857).

Fig. 4: SDS-PAGE Analysis Purified Wilm's Tumor Mouse Recombinant Monoclonal Antibody (rWT1/857). Confirmation of Purity and Integrity of Antibody

Fig. 5: Analysis of Protein Array containing more than 19,000 full-length human proteins using Wilm's Tumor Mouse Recombinant Monoclonal Antibody (rWT1/857). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 36-3376

Clone name :	rWT1/857
Clonality :	Monoclonal
Application :	IHC
Reactivity :	Human, Mouse, Rat

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Amount :	100 µg
Isotype :	Mouse IgG1, kappa
Content :	200 µg/ml of recombinant MAb Purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition :	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.


Gene :	WT1
Gene ID :	7490
Uniprot ID :	P19544
Alternative Name :	WT1; AWT1; FWT1; GUD; NPHS4; WAGR; Wilms tumor 1
Immunogen Information :	Recombinant full-length human WT1 protein

Recognizes a 47-55kDa-tumor suppressor protein, identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids, frequently found in subsets of sporadic Wilm's tumors.WT1, a sporadic and familial pediatric kidney tumor, is genetically heterogeneous. Wilm's tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The WT1 gene is normally expressed in fetal kidney and mesothelium, and its expression has been sÂµggested as a marker for Wilm's tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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