Anti-TTF-1 Monoclonal Antibody (Clone:IHC414)(Discontinued)

Product code: 44-1125

Clone name : IHC414
Clonality : Monoclonal
Application : IHC
Reactivity : Human

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Format : Purified
Amount : 1 ml
Purification : Protein A/G Chromatography
Storage condition : Store at 2°C - 8°C.
Gene : NKX2-1
Gene ID : 7080
Uniprot ID : P43699
Alternative Name : NKX2-1, NKX2A, TITF1, TTF1, Homeobox protein NK-2 homolog A, Thyroid nuclear factor 1, Thyroid transcription factor 1
Thyroid Transcription Factor 1 (TTF-1) is present in diencephalon, lung, and thyroid. Anti-TTF-1 stains thyroid and thyroid-derived tumors, and is therefore used for distinguishing lung adenocarcinoma from germ cell tumors, malignant mesothelioma, and metastatic carcinomas from organs other than the thyroid. It is also useful for distinguishing small cell lung carcinoma from lymphoid infiltrates, and pulmonary from non-pulmonary adenocarcinomas in malignant effusions. The ability to distinguish between pulmonary and non-pulmonary adenocarcinomas is particularly useful in identifying tumors that have metastasized to the brain.

Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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