PE Conjugated Anti-TRIM / TRAT1 Monoclonal Antibody (Clone:TRIM-04)
Figure 1:: Intracellular staining of human peripheral blood with mAb TRIM-04 PE
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| Amount : | 0.1 mg |
| Isotype : | Mouse IgG2a |
| Storage condition : | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. |
TRIM (T cell receptor-interacting molecule), also known as TRAT1 (T cell receptor associated transmembrane adaptor 1) is a 30 kDa protein expressed by T cells as a cystein-linked homodimer. It associates with TCR-CD3-zeta-chain complex and becomes phosphorylated by Src-family kinases. TRIM is potentially involved in negative regulation of TCR-mediated signaling, but its role remains unclear.
| Subcellular location: | Cytoplasm |
| Post transnational modification: | Auto-ISGylated. |
| Tissue Specificity: | Expressed in breast tumors (at protein level). Ubiquitous. |
| BioGrid: | 113500. 2393 interactions. |
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