Anti-TNAP APC (Clone : W8B2B10)

Product code: 30-2483

Clone name : W8B2B10
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : APC

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0.1 mg
$503.00 

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Amount : 0.1 mg
Isotype : Mouse IgG1
Purification : The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Content : 0.1 mg/ml
Formulation : Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : ALPL
Gene ID : 249
Alternative Name : Tissue Non-specific Alkaline Phosphatase, MSCA-1, liver/bone/kidney alkaline phosphatase,alkaline phosphatase, biomineralization associated
Immunogen Information : WERI-RB-1 retinoblastoma cell line

Tissue non-specific alkaline phosphatase (TNAP), also known as liver/bone/kidney alkaline phosphatase, or MSCA-1 (mesenchymal stem cell antigen 1) is a selective marker for the prospective isolation of bone marrow-derived mesenchymal stem cells and mesenchymal stem-like cells. It is expressed at high levels in liver, bone, kidney, or endometrium, as well as on embryonic stem cells (ESCs). TNAP also plays a role in bone mineralization. Mutations in TNAP gene are associated with hypercalcemia and skeletal defects (hypophosphatasia).
Specificity : The mouse monoclonal antibody W8B2B10 recognizes TNAP (tissue non-specific alkaline phosphatase), an ectoenzyme expressed mainly on embryonic stem cells, liver, bone, and kidney cells. This antibody is suitable for characterization of bone marrow-derived MSCs, iPSCs, and ESCs.

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