Anti-Thymidylate Synthase Monoclonal Antibody (Clone:IHC697)

Product code: 44-1189

Clone name : IHC697
Clonality : Monoclonal
Application : IHC
Reactivity : Human

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Available Pack Size(s)

  •   0.1 ml

  •  1 ml

  • $416.00 

  • $988.00 

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Format : Purified
Amount : 1 ml
Purification : Protein A/G Chromatography
Storage condition : Store at 2°C - 8°C.
Gene : TYMS
Gene ID : 7298
Uniprot ID : P04818
Alternative Name : TYMS, TS, OK/SW-cl.29, TSase

Thymidylate Synthase (TS) is a crucial enzyme responsible for the synthesis of 2'-deoxythymidine-5'-monophosphate (dTMP) a precursor for thymidylate which is necessary for DNA replication and repair from 2'-deoxyuridine-5'-monophosphate (dUMP). In terms of cancer, TS is an important target for cancer treatment as the inhibition of TS and therefore nucleotide synthesis necessary for cell growth has shown to be a vital part for successful treatment against colorectal, pancreatic and breast cancers.

Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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