Anti-TCR gamma/delta Monoclonal Antibody (Clone:V65)
Figure 1: Flow cytometry surface staining pattern of rat splenocytes stained using anti-rat TCR gamma/delta (V65) purified antibody
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Mouse IgG1 |
| Purification : | Purified by protein-A affinity chromatography |
| Storage condition : | Store at 2-8°C. Do not freeze. |
The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.
Flow Cytometry Recommended dilution:1 µg/ml
Immunoprecipitation Immunohistochemistry (frozen sections) Functional Application in vitro activation, in vivo depletion of gamma/delta T cells
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
| Subcellular location: | Cell projection, Cell projection |
| Post transnational modification: | Ubiquitinated by CBLB in activated T-cells. |
| BioGrid: | 247766. 3 interactions. |
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