FITC Conjugated Anti-TCR alpha/beta Monoclonal Antibody (Clone:R73)

Product code: 30-2071

Clone name : R73
Clonality : Monoclonal
Application : FACS
Reactivity : Non-Human Primates
Conjugate : FITC

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Size
Price
0.1 mg
$415.00 

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Amount : 0.1 mg
Isotype : Mouse IgG1
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : PTCRA
Gene ID : 171558
Uniprot ID : Q6ISU1
Alternative Name : PTCRA
Immunogen Information : Rat T blasts and erythrocytes

The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.

Subcellular location: Membrane
Tissue Specificity: Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.
BioGrid: 128144. 10 interactions.
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