PE Conjugated Anti-STRO-1 Monoclonal Antibody (Clone:STRO-1)

Product code: 30-2303

Clone name : STRO-1
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : PE

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0.1 mg
$468.00 

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Amount : 0.1 mg
Isotype : Mouse IgM
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Immunogen Information : Human CD34 positive bone marrow cells

STRO-1 is a cell surface antigen expressed by stromal elements in human bone marrow, identified by monoclonal antibody STRO-1. Approximately 10% of mononuclear cells, greater than 95% of which are nucleated erythroid precursors, are STRO-1 positive, whereas the CFU-GM (colony-forming unit granulocyte-macrophage), BFU-E (erythroid burst) and CFU-Mix (mixed colonies) committed progenitor cells are negative. CFU-F (fibroblast colony-forming cells) are present exclusively in the STRO-1 positive population. When plated under long-term bone marrow culture conditions, STRO-1 positive cells generate adherent cell layers containing multiple stromal cell types, including adipocytes, smooth muscle cells, osteoblasts, chondrocytes, and fibroblastic elements. In combination with glycophorin A, STRO-1 is a useful marker for identification of mesenchymal stem cells. STRO-1 and CD117 are markers for osteosarcoma cells.

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