Anti-SARS-CoV Spike (17aa Intermediate Domain)
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| Amount : | 0.1 mg |
| Content : | Concentration:0.5 mg/ml Formulation: This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative. |
| Storage condition : | This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at ?20°C?in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
Specificity: Rabbit Anti- Severe Acute Respiratory Syndrome Spike (SARS-CoV Spike) recognizes an epitope in the intermediate domain of SARS Spike. This polyclonal antibody was purified using affinity chromatography.
Background: A novel coronavirus has recently been identified as the causative agent of SARS-CoV.1-2 Coronaviruses are a major cause of upper respiratory diseases in humans.3 The genomes of these viruses are positive-stranded RNA approximately 27-31kb in length. SARS infection can be mediated by the binding of the viral spike protein, a glycosylated 139 kDa protein and the major surface antigen of the virus, to the angiotensin-converting enzyme 2 (ACE2) on target cells. This binding can be blocked by a soluble form of ACE2.4
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