Anti-pTHEMIS antibody(4F2), IgG1 Chimeric mAb
Figure 1. ELISA examination of DMC101054 specificity. The antibody at various concentrations was incubated in plates coated with either THEMIS or phosphorylated THEMIS (pTHEMIS), and a sigmoidal curve was developed only when using pTHEMIS, but not THEMIS, as capture antigen, indicating a specific binding of DMC101054 to pTHEMIS.
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Amount : | 100 µg |
Isotype : | Rabbit/Human Fc chimeric IgG1 |
Purification : | Purified from cell culture supernatant by affinity chromatography |
Content : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage condition : | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Uniprot ID : | Q8N1K5 |
Alternative Name : | THEMIS, C6orf190, C6orf207 |
This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants.
ELISA 1:5000-10000
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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