Anti-PD-L1 antibody(DM124), Rabbit mAb

Product code: 12-9298

Clone name : DM124
Clonality : Monoclonal
Application : ELISA, FACS
Reactivity : Human

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Size
Price
100 µg
$637.00 

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For estimated delivery dates, please contact us at [email protected]


Amount : 100 µg
Purification : Purified from cell culture supernatant by affinity chromatography
Content :
Not Sterile
Storage condition : Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Alternative Name : PDL1, CD274, B7-H1, PDCD1L1, PDCD1LG1

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants.

ELISA 1/5000-10000;FACS  1/100

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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