Anti-p57 kip2 Monoclonal Antibody (Clone:IHC057)
Figure 1: Immunohistochemical analysis of p57kip2 (IHC057) on Placenta
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| Format : | Purified |
| Amount : | 1 ml |
| Purification : | Protein A/G Chromatography |
| Storage condition : | Store at 2°C - 8°C. |
p57kip2, also known as p57, is a tumor suppressor protein that causes cell cycle arrest at G1 by binding G1 cyclin-CDK complexes. The p57kip2 gene is a potential tumor suppressor target as the gene is located in a chromosomal region implicated in sporadic cancers, Wilms' tumor, and Beckwith Wiedemann syndrome. Anti-p57kip2 labels many cytotrophoblast nuclei and stromal cells in normal placenta, and is useful in differentiating between complete hydatidiform mole and partial hydatidiform mole or hydropic abortion.
Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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