Anti-p40(IL-12/IL-23) monoclonal Antibody (Wezlana Biosimilar)
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| Amount : | 100 µg |
| Isotype : | IgG1,k |
| Content : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Reconstitute in sterile water. |
| Storage condition : | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized antibodies are shipped at ambient temperature. |
| Alternative Name : | Wezlana, west, Ustekinumab-auub |
Wezlana (Ustekinumab-auub) is a biosimilar to Stelera. The U.S. Food and Drug Administration approved Wezlana (ustekinumab-auub) as a biosimilar to and interchangeable with Stelara (ustekinumab) for multiple inflammatory diseases. Ustekinumab is a fully human IgG1 monoclonal antibody that binds with specificity to the shared p40 protein subunit of human cytokines interleukin IL-12 and IL-23, which are involved in immune and inflammatory responses. IL-12 and IL-23 are produced by activated antigen-presenting cells as secreted heterodimeric cytokines that bind to receptor complexes in natural killer cells and T cells. Ustekinumab can effectively neutralizing both human IL-12 (Th1)-mediated and IL-23 (Th17)-mediated cellular responses.
FACS 1:100
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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