Anti-p16 Monoclonal Antibody (Clone:IHC016)-Ready to Use(Discontinued)

Product code: 44-1059

Clone name : IHC016
Clonality : Monoclonal
Application : ELISA
Reactivity : Human

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For estimated delivery dates, please contact us at [email protected]


Amount : 7 ml
Isotype : Mouse IgG1
Purification : Protein A/G Chromatography
Content : Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Storage condition : Store at 2°C - 8°C. Do not freeze.
Gene : CDKN2A
Gene ID : 1029
Uniprot ID : P42771
Alternative Name : CDKN2A, CDKN2, MTS1
Immunogen Information : Recombinant human p16INK4A C-terminus protein

"The p16 (p16INK4A) protein is a cyclin-dependent kinase inhibitor that plays an important regulatory role in the cell cycle. By controlling the transition between the G1 and S phases through regulation of retinoblastoma protein, p16 decelerates cellular differentiation and therefore acts as a tumor suppressor, making it the key marker in several human cancers including head and neck cancer, perianal lesions, melanomas, gliomas, lymphomas, and some types of leukemia. p16 is also clinically indicated in carcinomas of the esophagus, pancreas, lung, biliary tract, liver, colon, and urinary bladder."

This product is available in ready to use format, hence no dilution is required.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Cytoplasm, Nucleus
Post transnational modification: Phosphorylation seems to increase interaction with CDK4.
Tissue Specificity: Widely expressed but not detected in brain or skeletal muscle. Isoform 3 is pancreas-specific.
BioGrid: 107463. 183 interactions.
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