Anti-OCT-2 (POU2F2) (B-Cell Marker) Monoclonal Antibody(Clone: 86839)

Name: Anti-OCT-2 (POU2F2) (B-Cell Marker) Monoclonal Antibody(Clone: 86839)
Brand: Abeomics
SKU: 36-2976
Price: 520.0000 USD
Availability: InStock
Rating: 4.2 (10 reviews)

Fig. 1: Formalin-fixed, paraffin-embedded human Lymph Node stained with Oct-2 Mouse Monoclonal Antibody (OCT2/2137).

Anti-OCT-2 (POU2F2) (B-Cell Marker) Monoclonal Antibody(Clone: 86839)

Roll over image to zoom in

Fig. 1: Formalin-fixed, paraffin-embedded human Lymph Node stained with Oct-2 Mouse Monoclonal Antibody (OCT2/2137).

Fig. 2: Formalin-fixed, paraffin-embedded human Tonsil stained with Oct-2 Mouse Monoclonal Antibody (OCT2/2137).

Fig. 3: Western Blot Analysis Ramos cell lysate using Oct-2 Mouse Monoclonal Antibody (OCT2/2137).

Fig. 4: Western Blot Analysis (A) Recombinant Protein (B) Daudi cell lysate Oct-2 Mouse Monoclonal Antibody (OCT2/2137).

Fig. 5: SDS-PAGE Analysis Purified Oct-2 Mouse Monoclonal Antibody (OCT2/2137). Confirmation of Integrity and Purity of Antibody.

Fig. 6: Analysis of Protein Array containing more than 19,000 full-length human proteins using Oct-2 Mouse Monoclonal Antibody (OCT2/2137) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 36-2976

Clone name :	Oct2-2137
Clonality :	Monoclonal
Application :	ELISA, WB, IHC
Reactivity :	Human

Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Write a review for this product on BioCompare

Get $20 gift card from Amazon

Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Amount :	100 µg
Isotype :	Mouse IgG1, kappa
Content :	200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition :	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.


Gene :	POU2F2
Gene ID :	5452
Uniprot ID :	P09086
Alternative Name :	Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Oct-2; Octamer-binding protein 2; Octamer-binding transcription factor 2; OTF-2; POU domain class 2 transcription factor 2; POU2F2
Immunogen Information :	Recombinant fragment of human OCT2 protein (around aa 112-297) (exact sequence is proprietary)

Oct-2 is a transcription factor of the POU homeo-domain family that binds to the Ig gene octamer sites, regulating B-cell-specific genes. Oct-2 expression can be used as a marker of B-cell lineage and differentiation. Germinal center B-cells, mantle B-cells, monocytoid B-cells, and plasma cells show high level expression of Oct-2. Additionally, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, plasmacytoma, Burkitt lymphoma, diffuse large cell lymphoma, diffuse large B-cell lymphoma, Hodgkin lymphoma display increased expression of Oct-2. Several studies of Oct-2 expression have shown a low level expression in pre-B, T-cell, myelomonocytic, and epithelial cell lines, whereas all mature B-cell lines have high levels of expression. In spite of scanty evidence for Oct-2 expression in T cells, it is believed that this factor participates in transcriptional regulation during T-cell activation.

ELISA (For coating, order antibody without BSA); Western Blot (1-2ug/ml); ,Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

There are currently no product reviews

Write a review on this product!