Anti-NTAL / LAB Polyclonal Antibody
Figure 1: Western Blotting analysis (non-reducing conditions) of mouse NTAL in mouse spleen tissue. Lane 1: immunostaining with polyclonal anti-NTAL antibody. Lane 2: immunostaining with polyclonal anti-mouse NTAL antibody (specific for N-terminal domain of mouse NTAL; )
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Rabbit IgG |
| Purification : | Purified from rabbit serum by affinity chromatography |
| Storage condition : | Store at 2-8°C. Do not freeze. |
| Immunogen Information : | Recombinant mouse NTAL (aa 30-203). |
NTAL (Non-T cell activation linker), also known as LAB (Linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.
Western Blotting Recommended dilution: 1 µg/ml
Positive control: mouse spleen
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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