Anti-NG2 / Chondroitin sulfate proteoglycan 4 Monoclonal Antibody (Clone:7.1)

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Product code: 30-1106

Clone name :	7.1
Clonality :	Monoclonal
Application :	FACS
Reactivity :	Human

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS MSDS

Format :	Purified
Amount :	0.1 mg
Isotype :	Mouse IgG1
Purification :	Purified by protein-A affinity chromatography
Storage condition :	Store at 2-8°C. Do not freeze.


Gene :	CSPG4
Gene ID :	1464
Uniprot ID :	Q6UVK1
Alternative Name :	CSPG4, MCSP
Immunogen Information :	Human bone marrow stromal cells infected with SV-40

NG2 / Chondroitin sulfate proteoglycan 4 is expressed on glial cell populations, but not on normal hepatopoietic cells. It is an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells, where it plays role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes, and supports signaling pathways important for tumor invasion and growth. NG2 also serves as an AML blast tumor marker associated with poor prognosis.

Subcellular location:	Cell membrane, Apical cell membrane, Cell projection, Cell surface
Post transnational modification:	Phosphorylation by PRKCA regulates its subcellular location and function in cell motility.
Tissue Specificity:	Detected only in malignant melanoma cells.
BioGrid:	107846. 13 interactions.