Anti-Nanog Monoclonal Antibody (Clone:IHC634)

Product code: 44-1054

Clone name : IHC634
Clonality : Monoclonal
Application : IHC
Reactivity : Human

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  •   0.1 ml

  •  0.5 ml

  • $388.00 

  • $719.00 

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Format : Purified
Amount : 0.5 ml
Isotype : Mouse IgG1
Purification : Protein A/G Chromatography
Content : Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
Storage condition : Store at 2°C - 8°C. Do not freeze.
Gene : NANOG
Gene ID : 79923
Uniprot ID : Q9H9S0
Alternative Name : NANOG
Immunogen Information : Recombinant Human Nanog

Nanog is a homeoprotein that functions with pluripotent factors such as Oct4 and Sox2 to maintain embryonic stem cell pluripotency. Expression of this protein has been noted in seminoma, dysgerminoma, embryonal carcinoma, and other undifferentiated germ cell tumors, while nanog expression is absent in normal adult organ tissues. Anti-Nanog may be useful in distinguishing between undifferentiated germ cell tumors and non-germ cell tumors.

Recommended dilutions: Immunohistochemical analysis: 1:100 - 1:200. However, this need to be optimized based on the research applications.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Nucleus
Tissue Specificity: Expressed in testicular carcinoma and derived germ cell tumors (at protein level). Expressed in fetal gonads, ovary and testis. Also expressed in ovary teratocarcinoma cell line and testicular embryonic carcinoma. Not expressed in many somatic organs and oocytes.
BioGrid: 123000. 226 interactions.
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