Anti-N-cadherin Monoclonal Antibody (Clone:IHC636)-Ready to Use(Discontinued)
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Format : | Predilute |
Amount : | 7 ml |
Purification : | Protein A/G Chromatography |
Storage condition : | Store at 2°C - 8°C. |
N-cadherin, also known as Cadherin-2 (CDH2) or Neural Cadherin (NCAD), is a transmembrane cell adhesion molecule that was originally detected in nervous tissue. It plays an important role in embryogenesis, being involved in gastrulation and neural crest development. N-cadherin is found is cancer cells and allows for transendothelial migration, which is a critical process in the metastasis of cancer. Overexpression and disorderly arrangement of N-cadherin has been noted in dilated cardiomyopathy. It has been suggested that, when considered in adjunct with the status of a number of additional cell-cell adhesion molecules, missense mutations in N-cadherin may be a potential indicator of obsessive-compulsive disorder and Tourette disorder.
This product is available in ready to use format, hence no dilution is required.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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