Anti-MyoD1 (Rhabdomyosarcoma Marker) Recombinant Rabbit Monoclonal Antibody (Clone:MYOD1/2075R)

Name: Anti-MyoD1 (Rhabdomyosarcoma Marker) Recombinant Rabbit Monoclonal Antibody (Clone:MYOD1/2075R)
Brand: Abeomics
SKU: 12-1220
Price: 520.0000 USD
Availability: InStock
Rating: 4.5 (10 reviews)

Figure 1: Formalin-fixed, paraffin-embedded human Rhabdomyosarcoma stained with MyoD1 Mouse Recombinant Monoclonal Antibody (MYOD1/2075R).

Anti-MyoD1 (Rhabdomyosarcoma Marker) Recombinant Rabbit Monoclonal Antibody (Clone:MYOD1/2075R)

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Figure 1: Formalin-fixed, paraffin-embedded human Rhabdomyosarcoma stained with MyoD1 Mouse Recombinant Monoclonal Antibody (MYOD1/2075R).

Figure 2: SDS-PAGE Analysis Purified MyoD1 Mouse Recombinant Monoclonal Antibody (MYOD1/2075R).

Figure 3:Analysis of Protein Array containing more than 19,000 full-length human proteins using MyoD1 Recombinant Rabbit Monoclonal Antibody (MYOD1/2075R). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Product code: 12-1220

Clone name :	MYOD1/2075R
Clonality :	Monoclonal
Application :	IHC
Reactivity :	Human

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Download TDS / Manual MSDS

Format :	Purified
Amount :	100 µg
Isotype :	Rabbit IgG
Purification :	Protein A/G
Content :	200µg/ml of recombinant MAb purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition :	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.


Gene :	MYOD1
Gene ID :	4654
Uniprot ID :	P15172
Alternative Name :	bHLHc1, Class C basic helix-loop-helix protein 1, Myoblast determination protein 1, Myogenic differentiation 1, Myogenic factor 3 (Myf-3), Myogenin D1, PUM
Immunogen Information :	Recombinant full-length human MyoD1 protein

Recognizes a phospho-protein of 45kDa, identified as MyoD1. This MAb does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas. Only nuclear staining should be considered as evidence of skeletal muscle differentiation.

Immunohistochemistry (Formalin-fixed) (1-2Âµg/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location:	Nucleus
Post transnational modification:	Methylation at Lys-104 by EHMT2/G9a inhibits myogenic activity.
BioGrid:	110737. 69 interactions.