Anti-Mycobacterium tuberculosis antigen GlcB Polyclonal Antibody
Figure 1:Western blotting analysis of polyclonal anti-Mycobacterium tuberculosis antigen GlcB. A) cell lysate of non-transfected E. coliB) cell lysate of GlcB-transfected E. coli
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Rabbit IgG |
| Purification : | Purified from rabbit serum by affinity chromatography |
| Storage condition : | Store at 2-8°C. Do not freeze. |
| Immunogen Information : | Recombinant Mycobacterium tuberculosis GlcB produced in E. coli |
The Mycobacterium tuberculosis antigen GlcB (malate synthase) catalyzes synthesis of malate from glyoxylate and acetyl-CoA. This reaction is part of the glyoxylate cycle, which allows the bacterium to derive its carbon requirements from two-carbon compounds by bypassing the two carbocylation steps of the cytric acid cycle. This enzyme is up-regulated in response to phagocytosis and it is a virulence or persistence factor.
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