Anti-Ms Ly6G Purified Low Endotoxin
Figure 1: Flow cytometry surface staining pattern of murine splenocyte suspension stained using anti-mouse Ly6G (RB6-8C5) purified antibody DAR PE.
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| Amount : | 0.1 mg |
| Purification : | Purified by protein-A affinity chromatography. |
| Content : | Concentration: 1 mg/ml Storage Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Storage condition : | Store at 2-8°C. Do not freeze. |
| Gene : | Ly6G |
| Gene ID : | 546644 |
| Uniprot ID : | A0A087WQF5 |
| Alternative Name : | lymphocyte antigen 6 complex, locus G Gr1, Gr-1, Ly-6G |
| Immunogen Information : | Murine granulocytes |
Ly6G is a component of the myeloid differentiation antigen Gr-1, together with Ly6C. Ly6G is a good marker for detection of peripheral neutrophils. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. Physiological role of Ly6G remains still unclear. Its treatment with antibodies in vivo leads to neutropenia and has inhibitory effect on local immune responses.
Specificity :The rat monoclonal antibody RB6-8C5 detects Ly6G component of Gr-1 antigen, a commonly used surface marker of neutrophils.
Functional application: Neutrophil depletion.
Immunoprecipitation: Recommended dilution: 1-2 µg / 100-500 µg of protein.
Western blotting: Recommended dilution: 1 µg/ml.
Flow cytometry: Recommended dilution: 1-4 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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