Anti-Mouse CD2 FITC (Clone : RM2-5)

Product code: 30-2627

Clone name : RM2-5
Clonality : Monoclonal
Application : FACS
Reactivity : Mouse
Conjugate : FITC

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0.1 mg
$433.00 

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Amount : 0.1 mg
Isotype : Rat IgG2b lambda
Purification : The purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Content : 0.5 mg/ml
Formulation : Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : CD2
Gene ID : 12481
Alternative Name : LFA-2, Ly37, Ly-37,CD2 molecule
Immunogen Information : Murine thymocytes
CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.
Specificity : The rat monoclonal antibody RM2-5 recognizes an extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells; also expressed by all thymocytes.
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