Anti-Mouse CD106 Azide Free Antibody (Clone : 429 (MVCAM.A))

Product code: 30-2664

Clone name : 429 (MVCAM.A)
Clonality : Monoclonal
Application : FACS , IP, IHC(F), Functional Assay
Reactivity : Mouse

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0.1 mg
$345.00 

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Format : Azide Free
Amount : 0.1 mg
Isotype : Rat IgG2a kappa
Purification : Purified by protein-A affinity chromatography
Content : 1 mg/ml
Formulation : Azide free phosphate buffered saline (PBS) solution, 0.2 µm filter sterilized
Storage condition : Store at 2-8°C. Do not freeze.
Gene : Vcam1
Gene ID : 22329
Alternative Name : Vcam-1,vascular cell adhesion molecule 1
Immunogen Information : Murine preadipose cell line PA6
CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking part in their positive selection and survival, as well as in adhesion, transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts. Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation, tumour cells can use overexpressed VCAM-1 to escape T cell immunity.
Specificity : The rat monoclonal antibody 429 (also known as MVCAM.A) recognizes an extracellular epitope of murine CD106, a 100-110 kDa type I membrane protein of the immunoglobulin superfamily, a crucial mediator of leukocyte adhesion, and a costimulation molecule.
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