Anti-MICA antibody(DM157), Rabbit mAb

Product code: 12-9330

Clone name : DM157
Clonality : Monoclonal
Application : ELISA, FACS
Reactivity : Human

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Size
Price
100 µg
$637.00 

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Amount : 100 µg
Purification : Purified from cell culture supernatant by affinity chromatography
Content :
Not Sterile
Storage condition : Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Alternative Name : MIC-A, PERB11.1

This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2014]

ELISA 1/5000-10000;FACS 1/100

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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