FITC Conjugated Anti-Ly6G Monoclonal Antibody (Clone:RB6-8C5)
Figure 1: Surface staining of murine splenocytes with anti-Ly-6G (RB6-8C5) FITC.
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| Amount : | 0.1 mg |
| Isotype : | Rat IgG2b |
| Storage condition : | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. |
Ly6G is a component of the myeloid differentiation antigen Gr-1, together with Ly6C. Ly6G is a good marker for detection of peripheral neutrophils. Expression of Gr-1 in bone marrow correlates with granulocyte differentiation and maturation. Physiological role of Ly6G remains still unclear. Its treatment with antibodies in vivo leads to neutropenia and has inhibitory effect on local immune responses.
| Subcellular location: | Cell surface, Cell membrane, Cell projection |
| Post transnational modification: | O-glycosylated. Contains sialic acid residues. |
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