Anti-JAM-A antibody(DMC278), IgG1 Chimeric mAb

Product code: 12-9221

Clone name : DMC278
Clonality : Monoclonal
Application : FACS
Reactivity : Human

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Size
Price
100 µg
$637.00 

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For estimated delivery dates, please contact us at [email protected]


Amount : 100 µg
Purification : Purified from cell culture supernatant by affinity chromatography
Content :
Not Sterile
Storage condition : Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Alternative Name : CD321, JAM,JAM1, JAMA, JCAM, KAT, PAM-1

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

FACS 1/100

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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