Anti-Insulin / IRDN (beta-Cell & Insulinoma Marker) Recombinant Rabbit Monoclonal Antibody (Clone:IRDN/1980R)

Product code: 12-1199

Clone name : IRDN/1980R
Clonality : Monoclonal
Application : IHC
Reactivity : Human, Mouse

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  •   20 µg

  •  100 µg

  • $270.00 

  • $520.00 

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Shipping Info:

For estimated delivery dates, please contact us at [email protected]


Format : Purified
Amount : 100 µg
Isotype : Rabbit IgG
Purification : Protein A/G
Content : 200µg/ml of recombinant MAb purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage condition : Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
Gene : INS
Gene ID : 3630
Uniprot ID : P01308
Alternative Name : IDDM2, ILPR, IRDN, MODY10, Proinsulin
Immunogen Information : Recombinant full-length human Insulin protein
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected throµgh the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.

Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Secreted
BioGrid: 109842. 13 interactions.
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