Anti-IL3RA / CD123 (Acute Myeloid Leukemia Marker) Monoclonal Antibody(Clone: IL3RA/2947R)
Fig. 1: Formalin-fixed, paraffin-embedded human Tonsil stained with IL3RA / CD123 Rabbit Recombinant Monoclonal Antibody (IL3RA/2947R).
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| Amount : | 100 µg |
| Isotype : | Rabbit IgG |
| Content : | 200 µg/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage condition : | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. |
| Gene : | IL3RA |
| Gene ID : | 3563 |
| Uniprot ID : | P26951 |
| Alternative Name : | CD123; hIL3Ra; IL-3R-alpha; IL-3RA; IL3RAX; IL3RAY; IL3RX; IL3RY; Interleukin-3 Receptor, alpha; Interleukin3 receptor; Interleukin3 receptor, Y-chromosomal |
| Immunogen Information : | Recombinant fragment of human IL3RA protein (around aa 26-171) (exact sequence is proprietary) |
CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.
ELISA (For coating, order antibody without BSA);,Immunohistochemistry (Formalin-fixed) (0.25-0.5ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0 for 45 min at 95°C followed by cooling at RT for 20 minutes),
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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