anti-IL-33 (human), mAb (IL33305B)

Product code: 29-1011

Clone name : IL33305B
Application : Functional Assay, ELISA, IHC
Reactivity : Human

Shipping Info:

For estimated delivery dates, please contact us at [email protected]

Write a review for this product on BioCompare
Get $20 gift card from Amazon
Size
Price

Available Pack Size(s)

  •   100 µg

  •  50 µg

  • $425.00 

  • $350.00 

Add to Wish List

Shipping Info:

For estimated delivery dates, please contact us at [email protected]


Amount : 50 µg
Isotype : Mouse IgG2a,k
Content : Concentration 1mg/ml Formulation: Liquid. 0.2 μm-filtered solution in PBS, pH 7.4. Contains no preservatives
Storage condition : Stable for at least 1 year after receipt when stored at -20°C.
Alternative Name : Interleukin-33; IL-1F11; NF-HEV
Immunogen Information : Recombinant human IL-33.

Recognizes human IL-33. Does not cross-react with mouse IL-33.Interleukin-33 (IL-33; HF-NEV; IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30kDa human IL33 is converted by CASP1 to a 18kDa protein. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1 (MAPK3)/ERK2 (MAPK1), p38(MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis

ELISA: (direct or indirect: 1:2'000-1:5'000) Functional Application (Blocking) Immunohistochemistry (paraffin sections (1:50-1:200)) Immunoprecipitation Western blot: (1:2'000-1:5'000 using ECL. Suggested blocking and dilution buffer is PBST with 0.05% Tween 20 and 5% skim milk. Suggested incubation time is 1 hour at rooom temperature). Optimal conditions should be determined individually for each application.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

There are currently no product reviews

Customers who purchased this product also purchased

Most viewed Products