Anti-IL-17RA antibody(DM125), Rabbit mAb
Figure 1. Flow cytometry analysis with Anti-IL-17RA (DM125) on Expi293 cells transfected with human IL17RA (Blue histogram)or Expi293 transfected with irrelevant protein (Red histogram).
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| Amount : | 100 µg |
| Purification : | Purified from cell culture supernatant by affinity chromatography |
| Content : | Not Sterile |
| Storage condition : | Store at -20°C for 12 months (Avoid repeated freezing and thawing) |
| Alternative Name : | CD217,CDw217,IL-17RA,IL17R,CANDF5,hIL-17R |
Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.
FACS 1/100
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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