Anti-IgE Monoclonal Antibody (Clone:BE5)

Product code: 30-1207

Clone name : BE5
Clonality : Monoclonal
Application : ELISA, FACS
Reactivity : Human

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0.1 mg
$363.00 

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Format : Purified
Amount : 0.1 mg
Isotype : Mouse IgG1
Purification : Purified by Protein A chromatography
Content : 1mg/ml, Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage condition : Store at 2-8°C. Do not freeze.
Gene : IGHE
Uniprot ID : P01854
Alternative Name : Immunoglobulin heavy constant epsilon
Immunogen Information : Purified human IgE.

Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days), it is stabilized after binding to its high affinity receptor. Unlike IgM- IgG- and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion.

Flow cytometry: Recommended dilution: 5 μg/ml.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Subcellular location: Secreted, Cell membrane
Post transnational modification: The secreted form sCD23 is produced by ADAM10-mediated ectodomain shedding.
BioGrid: 108502. 4 interactions.
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