Anti-Human CD316 MAb (Clone :8A12)
Fig1: Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD316 (8A12) purified antibody (concentration in sample 5 μg/ml, GAM APC).
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| Format : | Purified |
| Amount : | 0.1 mg (C100) |
| Isotype : | Mouse IgG2a |
| Purification : | Purified by protein-A affinity chromatography. |
| Content : | 1 mg/ml Formulation: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Storage condition : | Store at 2-8°C. Do not freeze. |
Specificity: The mouse monoclonal antibody 8A12 recognizes an extracellular epitope of CD316, a type I transmembrane glycoprotein, expressed mainly by lymphocytes, NK cells and in a broad range of tissues.
CD316 is an approximately 63 kDa transmembrane glycoprotein, which forms stable complexes with CD9, as well as with CD81. It seems that CD316 participates in regulation of cell polarity and motility, in cell proliferation, oocyte fertilization and tumor cell metastasis. It is expressed mainly by lymphocytes, NK cells and in a broad range of tissues, and associates with actin cytoskeleton.
Flow cytometry: Recommended dilution: 1-5 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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