Anti-Human CD263 APC (Clone : TRAIL-R3-02)
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| Amount : | 0.1 mg |
| Isotype : | Mouse IgG1 |
| Purification : | The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography. |
| Content : | 0.1 mg/ml Formulation : Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide |
| Storage condition : | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. |
| Gene : | TNFRSF10C |
| Gene ID : | 8794 |
| Alternative Name : | TNFRSF10C, DcR1, TRAIL-R3, TRID, LIT,TNF receptor superfamily member 10c |
| Immunogen Information : | TRAIL-R3 (aa 1-280) - hIgGhc fusion protein |
TRAIL-R3 (CD263, TR3, DcR1, LIT, TRID), expressed mainly on neutrophils, belongs to receptors of TRAIL, a TNF-like membrane cytotoxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R3, however, is a GPI-anchored protein that lacks cytoplasmic death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by competing for binding of TRAIL with death receptor 5 (DR5).
Specificity : The antibody TRAIL-R3-02 reacts with TRAIL-R3, a 35 kDa GPI-anchored extracellular membrane protein expressed mainly on neutrophils.
Specificity : The antibody TRAIL-R3-02 reacts with TRAIL-R3, a 35 kDa GPI-anchored extracellular membrane protein expressed mainly on neutrophils.
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