Anti-Human CD253 APC (Clone : 2E5)
Shipping Info:
For estimated delivery dates, please contact us at [email protected]
Amount : | 0.1 mg |
Isotype : | Mouse IgG1 |
Purification : | The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography. |
Content : | 0.1 mg/ml Formulation : Phosphate buffered saline (PBS) solution with 15 mM sodium azide |
Storage condition : | Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. |
Gene : | TNFSF10 |
Gene ID : | 8743 |
Alternative Name : | TRAIL, Apo-2 ligand, Apo-2L, TNFSF10, APO2L, TNLG6A,TNF superfamily member 10 |
Immunogen Information : | Recombinant soluble fragment (aa 95-281) of human TRAIL. |
Human CD253 / TRAIL (TNF-Related Apoptosis Inducing Ligand), also called Apo2, is a type II membrane protein from the TNF family. TRAIL is a cytotoxic protein which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL-induced apotosis, is achieved through binding to two dealth-signaling receptors, DR4 (CD261 / TRAIL-R1) and DR5 (CD262 / TRAIL-R2).
Specificity : The antibody 2E5 reacts with an extracellular epitope within C-terminal half of TRAIL (APO-2L), a 21 kDa cytotoxic protein, activator of rapid apoptosis in tumor cells. TRAIL is mainly expressed in spleen, lung, prostate and also in many other tissues.
Specificity : The antibody 2E5 reacts with an extracellular epitope within C-terminal half of TRAIL (APO-2L), a 21 kDa cytotoxic protein, activator of rapid apoptosis in tumor cells. TRAIL is mainly expressed in spleen, lung, prostate and also in many other tissues.
There are currently no product reviews
|