Anti-Human CD253 APC (Clone : 2E5)

Product code: 30-2613

Clone name : 2E5
Clonality : Monoclonal
Application : FACS
Reactivity : Human
Conjugate : APC

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0.1 mg
$468.00 

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Amount : 0.1 mg
Isotype : Mouse IgG1
Purification : The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Content : 0.1 mg/ml
Formulation : Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage condition : Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Gene : TNFSF10
Gene ID : 8743
Alternative Name : TRAIL, Apo-2 ligand, Apo-2L, TNFSF10, APO2L, TNLG6A,TNF superfamily member 10
Immunogen Information : Recombinant soluble fragment (aa 95-281) of human TRAIL.
Human CD253 / TRAIL (TNF-Related Apoptosis Inducing Ligand), also called Apo2, is a type II membrane protein from the TNF family. TRAIL is a cytotoxic protein which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL-induced apotosis, is achieved through binding to two dealth-signaling receptors, DR4 (CD261 / TRAIL-R1) and DR5 (CD262 / TRAIL-R2).
Specificity : The antibody 2E5 reacts with an extracellular epitope within C-terminal half of TRAIL (APO-2L), a 21 kDa cytotoxic protein, activator of rapid apoptosis in tumor cells. TRAIL is mainly expressed in spleen, lung, prostate and also in many other tissues.
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