Anti-Human CD226 Monoclonal Antibody (Clone:11A8) PE-Cy7 Conjugated
Figure 1: Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD226 (11A8) PE-Cy™7 antibody
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Format : | Purified |
Amount : | 100 tests |
Isotype : | Mouse IgG1 kappa |
Purification : | Purified by protein-A affinity chromatography |
Content : | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
Storage condition : | Store at 2-8°C. Do not freeze. |
CD226 is a type I transmembrane glycoprotein, which is expressed after activation on NK cells, platelets, monocytes, and some T cells. Its expression is increased in patients suffering from some autoimmune diseases or viral infections. CD226 is being phosphorylated on its cytoplasmic tail and interacts with LFA-1 complex (CD11a/CD18), resulting in calcium-independent intercellular contacts. Ligands for CD226 are CD155 and CD112.
Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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