Anti-Human CD133 Antibody (Clone : W6B3C1)

Product code: 30-2655

Clone name : W6B3C1
Clonality : Monoclonal
Application : FACS , WB, IHC
Reactivity : Human

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0.1 mg
$424.00 

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Format : Purified
Amount : 0.1 mg
Isotype : Mouse IgG1
Purification : Purified from cell culture supernatant by protein-A affinity chromatography
Content : 1 mg/ml
Formulation : Phosphate buffered saline (PBS) solution with 15 mM sodium azide
Storage condition : Store at 2-8°C. Do not freeze.
Gene : PROM1
Gene ID : 8842
Alternative Name : Prominin 1, PROM1, AC133, PROML1, STGD4,prominin 1
Immunogen Information : WERI-RB-1 retinoblastoma cell line
CD133 (prominin 1) is a 5-transmembrane glycoprotein with extracellular N- and intracellular C-terminus. CD133 function remains to be elucidated, but it can be used as a cancer stem cell marker. Its expression pattern in progenitor cells is similar to CD34, i.e. on hematopoietic stem cells in bone marrow, cord blood, neural stem cells, retinoblastoma, or endothelial precursor cells (not mature endothelial cells). It is being used for identification and isolation of hematopoietic stem cells, including isolation for stem cell transplantation. Expression of CD133 correlates with differentiation of human colon cancer cells.
Specificity : The mouse monoclonal antibody W6B3C1 recognizes the extracellular glycosylated epitope 1 on human CD133 (CD133/1), a 120 kDa glycoprotein of prominin family, expressed e.g. on progenitor cells. This antibody is important for identification of stem cells and tumor cells.
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