Anti-Human C5aR2 Antibody (Clone : 1D9-M12)
Figure 1 : Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human C5aR2 (1D9-M12) Purified antibody (concentration in sample 5,0 µg/ml, GAM APC).
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| Format : | Purified |
| Amount : | 0.1 mg |
| Isotype : | Mouse IgG2a kappa |
| Purification : | Purified by protein-A affinity chromatography |
| Content : | 1 mg/ml, Formulation : Phosphate buffered saline (PBS) solution with 15 mM sodium azide |
| Storage condition : | Store at 2-8°C. Do not freeze. |
| Gene : | C5AR2 |
| Gene ID : | 27202 |
| Alternative Name : | C5L2, GPR77, GPF77,complement component 5a receptor 2 |
| Immunogen Information : | L1.2 cells transfected with human C5aR2 |
C5aR2, also known as C5L2, is one of two receptors for C5a (anaphylatoxin). It is coexpressed with C5aR1 (CD88) in neutrophils, as well as e.g. in mast cells, astrocytes, or macrophages, and seems to have both pro-inflammatory and anti-inflammatory roles, depending on circumstances. Unlike CD88, C5aR2 is not coupled to G-protein, thus the modulatory role is more likely.
Specificity : The mouse monoclonal antibody 1D9-M12 recognizes an extracellular epitope on C5aR2 (C5L2), a C5a complement receptor, which is coexpressed with C5aR1 (CD88) in neutrophils, as well as e.g. in mast cells, astrocytes, or macrophages.
Flow cytometry: Recommended dilution: 2-6 µg/ml
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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