Anti-Human C3aR Mab (Clone: HC3aRZ8) Purified

Product code: 30-2882

Clone name : HC3aRZ8
Clonality : Monoclonal
Application : IHC, FACS
Reactivity : Human

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0.1 mg
$389.00 

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Amount : 0.1 mg
Isotype : Mouse IgG2b
Purification : Purified by protein-A affinity chromatography.
Content : 1.0 mg/ml
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage condition : Store at 2-8°C. Do not freeze.
Gene : C3AR1
Gene ID : 719
Uniprot ID : Q16581
Alternative Name : AZ3B, HNFAG09
Immunogen Information : Human C3aR transfectants

Specificity : The mouse monoclonal antibody HC3aRZ8 recognizes an extracellular epitope of C3aR, a transmembrane chemotactic receptor for C3a anaphylatoxin.

C3aR is a 7TM transmembrane protein associated with G proteins, and serves as a receptor for C3a complement fragment. It is expressed mainly on neutrophils, mast cells, basophils, eosinophils, dendritic cells, monocytes, and macrophages. Upon detection of its ligand, the activated C3aR signaling cascade results in degranulation, superoxide production, and chemotaxis.

Flow cytometry: Recommended dilution: 1-4 μg/ml.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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