Anti-Hu HER3 Purified

Product code: 30-2736

Clone name : H3Mab-17
Clonality : Monoclonal
Application : FACS
Reactivity : Human

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0.1 mg
$398.00 

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Format : Purified
Amount : 0.1 mg
Purification : Purified by protein-A affinity chromatography.
Content : Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage condition : Store at 2-8°C. Do not freeze.
Gene : ERBB3
Gene ID : 2065
Uniprot ID : P21860
Alternative Name : erb-b2 receptor tyrosine kinase 3 ERBB3, FERLK, LCCS2
Immunogen Information : HER3-transfected CHO cells
HER3 (ERBB3) is a transmembrane protein of the epidermal growth factor receptor family, although it does not have an active tyrosine kinase domain. It can bind its ligand, but for further signaling it needs heterodimerization with other receptor tyrosine kinases of EGFR family. Overexpression of HER3 has been observed in many carcinomas. Activity of HER3 can be modulated by one of its isoforms, that is secreted from the cell, as its lacks the transmembrane domain.
Specificity :The mouse monoclonal antibody H3Mab-17 recognizes an extracellular epitope on human HER3, a member of EGFR family of receptor tyrosine kinases, which is overexpressed in many cancers.

Flow cytometry: Recommended dilution: 1-5 µg/ml.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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