Anti-Hu CD49a Purified (Clone: TS2/7)
Figure 1: Separation of HeLa cells stained using anti-CD49a (TS2/7) purified antibody (GAM APC, red-filled) from HeLa cells unstained by primary antibody (GAM APC, black-dashed) in flow cytometry analysis (surface staining).
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| Format : | Purified |
| Amount : | 0.1 mg |
| Purification : | Purified by protein-A affinity chromatography. |
| Content : | Storage Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Storage condition : | Store at 2-8°C. Do not freeze. |
CD49a is the alpha 1 chain of VLA integrin complex (together with CD29, serving as the beta 1 chain), and is expressed on activated T cells, monocytes, NK cells, cultured neuronal cells, melanoma cells, mesenchymal cells (including smooth muscle cells), fibroblasts, hepatocytes, and microvascular endothelium. It binds to collagen IV and laminin 1. It is important for leukocyte migration into tissues. It is upregulated in inflammatory tissues, such as inflammed intestine.
Specificity :The mouse monoclonal antibody TS2/7 recognizes an extracellular epitope of CD49a, the alpha 1 chain of VLA integrin complex, that serves as an adhesion receptor for collagen IV and laminin 1.
Flow cytometry: Recommended dilution: 1-4 µg/ml.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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