Anti-Hu CD316 PE Mab(8A12)
Figure 1: Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD316 (8A12) PE antibody (10 μl reagent / 100 μl of peripheral whole blood).
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| Amount : | 100 Tests |
| Isotype : | Mouse IgG2a |
| Purification : | Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
| Content : | Formulation : Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| Storage condition : | Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze. |
Specificity: The mouse monoclonal antibody 8A12 recognizes an extracellular epitope of CD316, a type I transmembrane glycoprotein, expressed mainly by lymphocytes, NK cells and in a broad range of tissues.
CD316 is an approximately 63 kDa transmembrane glycoprotein, which forms stable complexes with CD9, as well as with CD81. It seems that CD316 participates in regulation of cell polarity and motility, in cell proliferation, oocyte fertilization and tumor cell metastasis. It is expressed mainly by lymphocytes, NK cells and in a broad range of tissues, and associates with actin cytoskeleton.
Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
For Research Use Only. Not for use in diagnostic/therapeutics procedures.
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