Anti-Hu CD272 Purified

Product code: 30-2811

Clone name : MIH26
Clonality : Monoclonal
Application : FACS
Reactivity : Human, Non-human primates

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0.1 mg
$398.00 

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Format : Purified
Amount : 0.1 mg
Purification : Purified by protein-A affinity chromatography.
Content : Concentration: 1 mg/ml
Storage Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Storage condition : Store at 2-8°C. Do not freeze.
Gene : BTLA
Gene ID : 151888
Uniprot ID : Q7Z6A9
Alternative Name : B and T lymphocyte associated BTLA1
Immunogen Information : cells transfected with human CD272
CD272, a type I transmembrane glycoprotein, contains in its intracellular domain two ITIM sequences, which are upon CD272 triggering phosphorylated and recruit SHP phosphatases to attenuate cell activation. CD272 is expressed on B and T lymphocytes, NK cells, dendritic cells, and macrophages, and its ligand is CD270. Defects in CD272-CD270 inhibitory mechanism lead to autoimmune diseases. Overexpression of CD272 is a marker of tolerant T cells.
Specificity :The mouse monoclonal antibody MIH26 recognizes an extracellular epitope of CD272, a transmembrane glycoprotein serving as a negative regulator of the activation in various leukocyte types.

Flow cytometry: Recommended dilution: 2-5 µg/ml.

For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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